Anemia is a lack of Red Blood Cells . One cause of low red blood cells is a reduction in Vitamin B12 either as a lack in the diet or the inability to be absorbed. This type of anemia is called pernicious anemia . It may be seen with persons taking proton pump inhibitors, or other medications that effect the parietal cells. Also may be seen with vegans, and patients with Chron’s disease. Another group affected are those who have undergone a Whipple procedure surgery.
Upon examination, patients may demonstrate a swollen tongue changes. Hair may depigmentation. Neurological findings include posterior spinal chord abnormalities such as the inability to sense vibration and/or the inability to detect the location of the arms and legs. Leg spasticity and incontinence has been reported
Lab studies will demonstrate macrocytic anemia.
Treatment is cyanobalamin (Vitamin B12 shots).