Chagas Disease is an illness caused by a protozoa called Trypanosoma Cruzi. Classically, T Cruzi enters a person via an insect called the “kissing bug.” The bite from the kissing bug may cause an eye swelling called Romana sign. At first, infected persons may have fever, malaise and tachycardia. As the illness progresses to the chronic phase, heart arrhythmia and congestive heart failure develop. Patients may also develop blood clots and an enlarged colon. There is no vaccine but good preventive measures include insecticides and nets at bedtime.